22^nd meeting of National Biosafety Committee (NBC) was convened on Wednesday 04^th November, 2020 in the Committee Room of Pakistan Environmental Protection Agency, Ministry of Climate Change, Islamabad. The Secretary, Ministry of Climate Change Ms. Naheed S. Durrani Chaired the meeting. A total Forty-nine (49) Genetically Modified Organisms (MGOs) related cases were discussed and decided in the meeting. Among these sixteen (16) cases were of laboratory genetic manipulation work twenty-eight (28) cases of field trials and five (05) cases of commercialization.